李石洋，教授，博士生导师。国家高层次人才引进计划入选者、国家重点研发计划青年项目首席科学家、山东省泰山学者青年专家、山东大学杰出中青年学者。

研究方向：胃肠道黏膜疾病（炎症、感染及肿瘤）中免疫系统的应答和调控机制。通过高通量测序等手段，在分子水平探索神经/内分泌系统对黏膜免疫细胞的分子调控机制。

联系方式：lishiyang2019(AT)hotmail.com  

教育工作经历

2019.08至今  山东大学 黏膜免疫学 教授

2018.09-2019.07   佛罗里达大学（美国） 黏膜免疫学 研究助理授

2015.12-2018.09   佛罗里达大学（美国） 黏膜免疫学 博后

2013.08-2015.11   西北大学（美国） 黏膜免疫学 博士后

2008.08-2013.06   南开大学 生物化学与分子生物学 博士生（博士）

2004.08-2008.06   南开大学 生物科学 本科生（学士）

论文成果

Li, S., Bostick, J.W., Qu, J., Zhang, B., Urban, J.F., Avram, D., Zhou, L. (2018) Aryl Hydrocarbon Receptor Signaling Cell-intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function. Immunity 49(5): 915-928.

Li, S., Heller, J.J., Bostick, J.W., Lee, A., Schjerven, H., Kastner, P., Zhou, L. (2016) Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway. Immunity 45(1):185-197.

Li, S., Bostick, J.W., Zhou, L. (2018) Regulation of Innate Lymphoid Cells by Aryl Hydrocarbon Receptor. Front. Immunol. 8:1909. doi: 10.3389/fimmu.2017.01909.

He, H.*, Li, S.*, Wang, S., Hu, M., Cao, Y., Wang, C. Y. (2012) Manipulation of cellular light from green fluorescent protein by a femtosecond laser. Nature Photonics 6(10):651-6. (*co-first author)

Li, S., Du, M., Lan, B., Liu, Y., Yang, Y., Zhang, C., Cao, Y. (2013) The N-terminal 20 amino acid region of guanine nucleotide exchange factor Vav1 plays a distinguished role in T cell receptor mediated calcium signaling. J. Biol. Chem. 288(6):3777-85.

Heller, J. J., Schjerven, H., Li, S., Lee, A., Qiu, J., Chen, Z. M., Smale, S.T., Zhou, L. (2014) Restriction of IL-22-producing T Cell Responses and Differential Regulation of Treg compartments by Zinc finger transcription factor Ikaros. J. Immunol. 193(8):3934-46.

Ye, J., Qiu, J., Bostick, J. W., Ueda, A., Schjerven, H., Li, S., Jobin, C., Chen, Z. E., Zhou, L. (2017) The Aryl Hydrocarbon Receptor Preferentially Marks and Promotes Gut Regulatory T Cells. Cell reports 21(8):2277-90.

Wang, Y., He, H., Li, S., Liu, D., Lan, B., Hu, M., Cao, Y., and Wang, C. (2014) All-optical regulation of gene expression in targeted cells. Scientific reports 4, 5346.

He, H., Wang, S., Li, X., Li, S., Hu, M., Cao, Y., Wang, C.Y. (2012) Ca2+ waves across gaps in non-excitable cells induced by femtosecond laser exposure. Appl. Phys. Lett. 100, 173704.

Yin, J., Wan, Y., Li, S., Du, M., Zhang, C., Zhou, X., Cao, Y. (2011) The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cells. Acta Pharmacol Sin. 32(1):99-107.